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Set 1: Species Homo sapiens Tissue Uterus;;Endometrium;;Secretory (Luteal);;Early (Pre-receptive) Condition Normal  Top 10            Top 100            All genes            References  Expressed genes Gene Score GO annotation CLDN4 2 BP    MF    CC biological_process calcium-independent cell-cell adhesion female pregnancy response to progesterone stimulus cellular_component apical plasma membrane apicolateral plasma membrane basal plasma membrane cell junction more... integral to membrane integral to plasma membrane lateral plasma membrane membrane plasma membrane tight junction less... molecular_function identical protein binding structural molecule activity transmembrane signaling receptor activity LIF 2 BP    MF    CC biological_process blood vessel remodeling decidualization embryo implantation immune response more... leukemia inhibitory factor signaling pathway lung alveolus development lung lobe morphogenesis lung vasculature development maternal process involved in female pregnancy multicellular organismal development muscle organ morphogenesis negative regulation of ERK1 and ERK2 cascade negative regulation of angiogenesis negative regulation of cell proliferation negative regulation of hormone secretion negative regulation of meiosis neuron development organ regeneration positive regulation of MAPKKK cascade positive regulation of astrocyte differentiation positive regulation of cell proliferation positive regulation of corticotropin secretion positive regulation of macrophage differentiation positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis positive regulation of neuron projection development positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation of STAT protein positive regulation of peptidyl-tyrosine phosphorylation positive regulation of transcription from RNA polymerase II promoter positive regulation of tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein regulation of cell differentiation regulation of metanephric nephron tubule epithelial cell differentiation retina development in camera-type eye spongiotrophoblast differentiation stem cell maintenance transdifferentiation trophoblast giant cell differentiation less... cellular_component extracellular region extracellular space molecular_function cytokine activity growth factor activity leukemia inhibitory factor receptor binding receptor binding more... BMP4 2 BP    MF    CC biological_process BMP signaling pathway BMP signaling pathway involved in heart induction BMP signaling pathway involved in nephric duct formation BMP signaling pathway involved in renal system segmentation more... BMP signaling pathway involved in ureter morphogenesis SMAD protein signal transduction activation of MAPKK activity angiogenesis anterior/posterior axis specification blood vessel development blood vessel endothelial cell proliferation involved in sprouting angiogenesis branching involved in ureteric bud morphogenesis branching morphogenesis of a tube bronchus development bud dilation involved in lung branching bud elongation involved in lung branching camera-type eye morphogenesis cardiac septum development cellular response to dexamethasone stimulus cellular response to growth factor stimulus chondrocyte differentiation cloacal septation cranial suture morphogenesis deltoid tuberosity development dorsal/ventral neural tube patterning embryonic cranial skeleton morphogenesis embryonic hindlimb morphogenesis embryonic morphogenesis embryonic skeletal joint morphogenesis endocardial cushion development endochondral ossification epithelial cell proliferation involved in lung morphogenesis epithelial tube branching involved in lung morphogenesis epithelial-mesenchymal cell signaling epithelium development erythrocyte differentiation germ cell development glomerular capillary formation glomerular visceral epithelial cell development growth hemopoietic progenitor cell differentiation inner ear receptor cell differentiation intermediate mesodermal cell differentiation kidney development lens induction in camera-type eye lung alveolus development lung morphogenesis lymphoid progenitor cell differentiation mammary gland formation mesenchymal cell proliferation involved in ureteric bud development mesenchymal to epithelial transition involved in metanephros morphogenesis mesodermal cell fate determination mesonephros development metanephric collecting duct development negative regulation of MAP kinase activity negative regulation of T cell differentiation in thymus negative regulation of apoptosis negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway negative regulation of branching involved in ureteric bud morphogenesis negative regulation of cell cycle negative regulation of cell death negative regulation of cell proliferation negative regulation of cell proliferation involved in heart morphogenesis negative regulation of chondrocyte differentiation negative regulation of epithelial cell proliferation negative regulation of glomerular mesangial cell proliferation negative regulation of glomerulus development negative regulation of immature T cell proliferation in thymus negative regulation of mesenchymal cell proliferation involved in ureter development negative regulation of metanephric S-shaped body morphogenesis negative regulation of metanephric comma-shaped body morphogenesis negative regulation of mitosis negative regulation of myoblast differentiation negative regulation of oligodendrocyte differentiation negative regulation of phosphorylation negative regulation of prostatic bud formation negative regulation of striated muscle tissue development negative regulation of thymocyte apoptosis negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-dependent neural tube closure neuron fate commitment odontogenesis odontogenesis of dentine-containing tooth organ induction osteoblast differentiation ovarian follicle development pituitary gland development positive chemotaxis positive regulation of BMP signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of SMAD protein import into nucleus positive regulation of apoptosis positive regulation of bone mineralization positive regulation of branching involved in lung morphogenesis positive regulation of branching involved in ureteric bud morphogenesis positive regulation of cardiac muscle fiber development positive regulation of cartilage development positive regulation of cell death positive regulation of collagen biosynthetic process positive regulation of endothelial cell differentiation positive regulation of endothelial cell migration positive regulation of endothelial cell proliferation positive regulation of kidney development positive regulation of neuron differentiation positive regulation of ossification positive regulation of osteoblast differentiation positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of protein phosphorylation positive regulation of smooth muscle cell proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription, DNA-dependent post-embryonic development prostate gland morphogenesis protein localization to nucleus pulmonary artery endothelial tube morphogenesis regulation of branching involved in prostate gland morphogenesis regulation of pathway-restricted SMAD protein phosphorylation regulation of smooth muscle cell differentiation renal system development renal system process response to estradiol stimulus response to glucocorticoid stimulus response to mechanical stimulus response to organic cyclic compound response to retinoic acid retina development in camera-type eye secondary heart field specification smooth muscle tissue development smoothened signaling pathway specification of organ position specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway steroid hormone mediated signaling pathway telencephalon development telencephalon regionalization tendon cell differentiation tongue morphogenesis trachea development trachea formation ureter epithelial cell differentiation ureter smooth muscle cell differentiation ureteric bud development less... cellular_component cytoplasm extracellular region extracellular space membrane-bounded vesicle more... proteinaceous extracellular matrix less... molecular_function BMP receptor binding chemoattractant activity cytokine activity growth factor activity more... heparin binding protein binding protein homodimerization activity less... KRT7 2 BP    MF    CC biological_process DNA replication cytoskeleton organization interphase interspecies interaction between organisms more... regulation of translation less... cellular_component Golgi apparatus cytoplasm intermediate filament keratin filament more... nucleolus nucleus less... molecular_function protein binding structural molecule activity FLT4 2 BP    MF    CC biological_process blood vessel morphogenesis lymph vessel development positive regulation of cell growth positive regulation of cell proliferation more... protein phosphorylation regulation of blood vessel remodeling sprouting angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway vascular endothelial growth factor receptor signaling pathway less... cellular_component integral to plasma membrane membrane plasma membrane molecular_function ATP binding growth factor binding nucleotide binding protein binding more... protein phosphatase binding protein tyrosine kinase activity receptor activity transferase activity, transferring phosphorus-containing groups transmembrane receptor protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity less... IGF1 2 BP    MF    CC biological_process DNA replication Ras protein signal transduction Type I pneumocyte differentiation Type II pneumocyte differentiation more... anti-apoptosis blood coagulation blood vessel remodeling bone mineralization involved in bone maturation branching morphogenesis of a tube cellular component movement chondroitin sulfate proteoglycan biosynthetic process exocrine pancreas development glial cell differentiation glycolate metabolic process lung alveolus development lung lobe morphogenesis lung vasculature development mammary gland development muscle hypertrophy muscle organ development myoblast differentiation myoblast proliferation myotube cell development negative regulation of ERK1 and ERK2 cascade negative regulation of androgen receptor signaling pathway negative regulation of cell proliferation negative regulation of release of cytochrome c from mitochondria negative regulation of smooth muscle cell apoptosis nervous system development phosphatidylinositol-mediated signaling platelet activation platelet degranulation positive regulation of DNA binding positive regulation of DNA replication positive regulation of MAPKKK cascade positive regulation of Ras protein signal transduction positive regulation of activated T cell proliferation positive regulation of calcineurin-NFAT signaling pathway positive regulation of cardiac muscle hypertrophy positive regulation of cell proliferation positive regulation of cerebellar granule cell precursor proliferation positive regulation of epithelial cell proliferation positive regulation of fibroblast proliferation positive regulation of glucose import positive regulation of glycogen biosynthetic process positive regulation of glycolysis positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of mitosis positive regulation of osteoblast differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase cascade positive regulation of protein import into nucleus, translocation positive regulation of protein kinase B signaling cascade positive regulation of smooth muscle cell migration positive regulation of smooth muscle cell proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription, DNA-dependent positive regulation of tyrosine phosphorylation of Stat5 protein prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis prostate gland epithelium morphogenesis prostate gland growth prostate gland stromal morphogenesis proteoglycan biosynthetic process regulation of establishment or maintenance of cell polarity regulation of multicellular organism growth regulation of protein metabolic process regulation of protein phosphorylation satellite cell maintenance involved in skeletal muscle regeneration signal transduction skeletal system development water homeostasis less... cellular_component extracellular region extracellular space insulin-like growth factor binding protein complex platelet alpha granule lumen more... molecular_function growth factor activity hormone activity insulin receptor binding insulin-like growth factor receptor binding more... integrin binding protein binding less... Not detected genes Gene Score GO annotation Expressed genes Gene Score GO annotation CLDN4 2 BP    MF    CC biological_process calcium-independent cell-cell adhesion female pregnancy response to progesterone stimulus cellular_component apical plasma membrane apicolateral plasma membrane basal plasma membrane cell junction more... integral to membrane integral to plasma membrane lateral plasma membrane membrane plasma membrane tight junction less... molecular_function identical protein binding structural molecule activity transmembrane signaling receptor activity LIF 2 BP    MF    CC biological_process blood vessel remodeling decidualization embryo implantation immune response more... leukemia inhibitory factor signaling pathway lung alveolus development lung lobe morphogenesis lung vasculature development maternal process involved in female pregnancy multicellular organismal development muscle organ morphogenesis negative regulation of ERK1 and ERK2 cascade negative regulation of angiogenesis negative regulation of cell proliferation negative regulation of hormone secretion negative regulation of meiosis neuron development organ regeneration positive regulation of MAPKKK cascade positive regulation of astrocyte differentiation positive regulation of cell proliferation positive regulation of corticotropin secretion positive regulation of macrophage differentiation positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis positive regulation of neuron projection development positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation of STAT protein positive regulation of peptidyl-tyrosine phosphorylation positive regulation of transcription from RNA polymerase II promoter positive regulation of tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein regulation of cell differentiation regulation of metanephric nephron tubule epithelial cell differentiation retina development in camera-type eye spongiotrophoblast differentiation stem cell maintenance transdifferentiation trophoblast giant cell differentiation less... cellular_component extracellular region extracellular space molecular_function cytokine activity growth factor activity leukemia inhibitory factor receptor binding receptor binding more... BMP4 2 BP    MF    CC biological_process BMP signaling pathway BMP signaling pathway involved in heart induction BMP signaling pathway involved in nephric duct formation BMP signaling pathway involved in renal system segmentation more... BMP signaling pathway involved in ureter morphogenesis SMAD protein signal transduction activation of MAPKK activity angiogenesis anterior/posterior axis specification blood vessel development blood vessel endothelial cell proliferation involved in sprouting angiogenesis branching involved in ureteric bud morphogenesis branching morphogenesis of a tube bronchus development bud dilation involved in lung branching bud elongation involved in lung branching camera-type eye morphogenesis cardiac septum development cellular response to dexamethasone stimulus cellular response to growth factor stimulus chondrocyte differentiation cloacal septation cranial suture morphogenesis deltoid tuberosity development dorsal/ventral neural tube patterning embryonic cranial skeleton morphogenesis embryonic hindlimb morphogenesis embryonic morphogenesis embryonic skeletal joint morphogenesis endocardial cushion development endochondral ossification epithelial cell proliferation involved in lung morphogenesis epithelial tube branching involved in lung morphogenesis epithelial-mesenchymal cell signaling epithelium development erythrocyte differentiation germ cell development glomerular capillary formation glomerular visceral epithelial cell development growth hemopoietic progenitor cell differentiation inner ear receptor cell differentiation intermediate mesodermal cell differentiation kidney development lens induction in camera-type eye lung alveolus development lung morphogenesis lymphoid progenitor cell differentiation mammary gland formation mesenchymal cell proliferation involved in ureteric bud development mesenchymal to epithelial transition involved in metanephros morphogenesis mesodermal cell fate determination mesonephros development metanephric collecting duct development negative regulation of MAP kinase activity negative regulation of T cell differentiation in thymus negative regulation of apoptosis negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway negative regulation of branching involved in ureteric bud morphogenesis negative regulation of cell cycle negative regulation of cell death negative regulation of cell proliferation negative regulation of cell proliferation involved in heart morphogenesis negative regulation of chondrocyte differentiation negative regulation of epithelial cell proliferation negative regulation of glomerular mesangial cell proliferation negative regulation of glomerulus development negative regulation of immature T cell proliferation in thymus negative regulation of mesenchymal cell proliferation involved in ureter development negative regulation of metanephric S-shaped body morphogenesis negative regulation of metanephric comma-shaped body morphogenesis negative regulation of mitosis negative regulation of myoblast differentiation negative regulation of oligodendrocyte differentiation negative regulation of phosphorylation negative regulation of prostatic bud formation negative regulation of striated muscle tissue development negative regulation of thymocyte apoptosis negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-dependent neural tube closure neuron fate commitment odontogenesis odontogenesis of dentine-containing tooth organ induction osteoblast differentiation ovarian follicle development pituitary gland development positive chemotaxis positive regulation of BMP signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of SMAD protein import into nucleus positive regulation of apoptosis positive regulation of bone mineralization positive regulation of branching involved in lung morphogenesis positive regulation of branching involved in ureteric bud morphogenesis positive regulation of cardiac muscle fiber development positive regulation of cartilage development positive regulation of cell death positive regulation of collagen biosynthetic process positive regulation of endothelial cell differentiation positive regulation of endothelial cell migration positive regulation of endothelial cell proliferation positive regulation of kidney development positive regulation of neuron differentiation positive regulation of ossification positive regulation of osteoblast differentiation positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of protein phosphorylation positive regulation of smooth muscle cell proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription, DNA-dependent post-embryonic development prostate gland morphogenesis protein localization to nucleus pulmonary artery endothelial tube morphogenesis regulation of branching involved in prostate gland morphogenesis regulation of pathway-restricted SMAD protein phosphorylation regulation of smooth muscle cell differentiation renal system development renal system process response to estradiol stimulus response to glucocorticoid stimulus response to mechanical stimulus response to organic cyclic compound response to retinoic acid retina development in camera-type eye secondary heart field specification smooth muscle tissue development smoothened signaling pathway specification of organ position specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway steroid hormone mediated signaling pathway telencephalon development telencephalon regionalization tendon cell differentiation tongue morphogenesis trachea development trachea formation ureter epithelial cell differentiation ureter smooth muscle cell differentiation ureteric bud development less... cellular_component cytoplasm extracellular region extracellular space membrane-bounded vesicle more... proteinaceous extracellular matrix less... molecular_function BMP receptor binding chemoattractant activity cytokine activity growth factor activity more... heparin binding protein binding protein homodimerization activity less... KRT7 2 BP    MF    CC biological_process DNA replication cytoskeleton organization interphase interspecies interaction between organisms more... regulation of translation less... cellular_component Golgi apparatus cytoplasm intermediate filament keratin filament more... nucleolus nucleus less... molecular_function protein binding structural molecule activity FLT4 2 BP    MF    CC biological_process blood vessel morphogenesis lymph vessel development positive regulation of cell growth positive regulation of cell proliferation more... protein phosphorylation regulation of blood vessel remodeling sprouting angiogenesis transmembrane receptor protein tyrosine kinase signaling pathway vascular endothelial growth factor receptor signaling pathway less... cellular_component integral to plasma membrane membrane plasma membrane molecular_function ATP binding growth factor binding nucleotide binding protein binding more... protein phosphatase binding protein tyrosine kinase activity receptor activity transferase activity, transferring phosphorus-containing groups transmembrane receptor protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity less... IGF1 2 BP    MF    CC biological_process DNA replication Ras protein signal transduction Type I pneumocyte differentiation Type II pneumocyte differentiation more... anti-apoptosis blood coagulation blood vessel remodeling bone mineralization involved in bone maturation branching morphogenesis of a tube cellular component movement chondroitin sulfate proteoglycan biosynthetic process exocrine pancreas development glial cell differentiation glycolate metabolic process lung alveolus development lung lobe morphogenesis lung vasculature development mammary gland development muscle hypertrophy muscle organ development myoblast differentiation myoblast proliferation myotube cell development negative regulation of ERK1 and ERK2 cascade negative regulation of androgen receptor signaling pathway negative regulation of cell proliferation negative regulation of release of cytochrome c from mitochondria negative regulation of smooth muscle cell apoptosis nervous system development phosphatidylinositol-mediated signaling platelet activation platelet degranulation positive regulation of DNA binding positive regulation of DNA replication positive regulation of MAPKKK cascade positive regulation of Ras protein signal transduction positive regulation of activated T cell proliferation positive regulation of calcineurin-NFAT signaling pathway positive regulation of cardiac muscle hypertrophy positive regulation of cell proliferation positive regulation of cerebellar granule cell precursor proliferation positive regulation of epithelial cell proliferation positive regulation of fibroblast proliferation positive regulation of glucose import positive regulation of glycogen biosynthetic process positive regulation of glycolysis positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of mitosis positive regulation of osteoblast differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase cascade positive regulation of protein import into nucleus, translocation positive regulation of protein kinase B signaling cascade positive regulation of smooth muscle cell migration positive regulation of smooth muscle cell proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription, DNA-dependent positive regulation of tyrosine phosphorylation of Stat5 protein prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis prostate gland epithelium morphogenesis prostate gland growth prostate gland stromal morphogenesis proteoglycan biosynthetic process regulation of establishment or maintenance of cell polarity regulation of multicellular organism growth regulation of protein metabolic process regulation of protein phosphorylation satellite cell maintenance involved in skeletal muscle regeneration signal transduction skeletal system development water homeostasis less... cellular_component extracellular region extracellular space insulin-like growth factor binding protein complex platelet alpha granule lumen more... molecular_function growth factor activity hormone activity insulin receptor binding insulin-like growth factor receptor binding more... integrin binding protein binding less... Not detected genes Gene Score GO annotation Expressed genes Gene Score CLDN4 2 LIF 2 BMP4 2 KRT7 2 FLT4 2 IGF1 2 Not detected genes Gene Score Identifiers Repository Data-sets 19557595 PubMed 1 Expressed(6) Not detected(0)